Accidental exposure to Burkholderia pseudomallei: awareness is also needed for urine specimens
نویسندگان
چکیده
منابع مشابه
Management of Accidental Laboratory Exposure to Burkholderia pseudomallei and B. mallei
The gram-negative bacillus Burkholderia pseudomallei is a saprophyte and the cause of melioidosis. Natural infection is most commonly reported in northeast Thailand and northern Australia but also occurs in other parts of Asia, South America, and the Caribbean. Melioidosis develops after bacterial inoculation or inhalation, often in relation to occupational exposure in areas where the disease i...
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Increasing evidence has shown that small-molecule chemistry in microbes (i.e., secondary metabolism) can modulate the microbe-host response in infection and pathogenicity. The bacterial disease melioidosis is conferred by the highly virulent, antibiotic-resistant pathogen Burkholderia pseudomallei (BP). Whereas some macromolecular structures have been shown to influence BP virulence (e.g., secr...
متن کاملFatal Burkholderia pseudomallei septicaemia.
Melioidosis, the infection caused by the saprophytic bacterium Burkholderia pseudomallei, is endemic in south-east Asia and northern Australia [1]. Sporadic cases have been reported from the Indian subcontinent and it is an emerging infection in India [2]. A low prevalence of antibodies against melioidosis among hospitalassociated groups in Colombo had been reported in 1976 [3], as well as a re...
متن کاملComparison of TaqMan PCR assays for detection of the melioidosis agent Burkholderia pseudomallei in clinical specimens.
Melioidosis is an emerging infectious disease caused by the soil bacterium Burkholderia pseudomallei. In diagnostic and forensic settings, molecular detection assays need not only high sensitivity with low limits of detection but also high specificity. In a direct comparison of published and newly developed TaqMan PCR assays, we found the TTS1-orf2 assay to be superior in detecting B. pseudomal...
متن کاملMonoclonal Antibody-Based Immunofluorescence Microscopy for the Rapid Identification of Burkholderia pseudomallei in Clinical Specimens
The diagnosis of melioidosis depends on the culture of Burkholderia pseudomallei, which takes at least 48 hours. We used a polyclonal-FITC-based immunofluorescence microscopic assay (Pab-IFA) on clinical samples to provide a rapid presumptive diagnosis. This has limitations including photobleaching and batch-to-batch variability. This study evaluated an IFA based on a monoclonal antibody specif...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2020
ISSN: 1198-743X
DOI: 10.1016/j.cmi.2019.10.013